Many volunteers around the world are committed to raise funds for cancer research and cancer charities. Many of the hundreds of thousands of jobs in the industry as carers, or research, the prescription, diagnosis and drug production. Large companies spend fortunes on cancer research. After so long and so many billions, what is cancer research reveal?
There has been steady progress in the understanding of cancer, but little progress in its treatment. Modern cancer research began in 1940 and '50, when scientists isolated substances that kill cancer cells growing in laboratory cell culture dish or leukemia in mice. early successes in chemotherapy set the pace and got a lot of media, although they were only 5% of cancer treatments at most.
Serving humanity by solving its major diseases has a celebrity status, there are a lot of congratulations and an air of Hollywood involved in these things. Cancer Research is a high activity level and sometimes scientific treatment found that the recognition of gain is large, such as HPV-16 trial, but only applies himself to the treatment of a small percentage of cancers. media hype is part of the problem of how we see cancer. The first discoveries created an expectation that there was a cure all treatments, a "magic formula" that would make its discoverer famous for the treatment of cancer worldwide. The idea comes in part from aspirin, the original ball that finds its way by magic and decreases pain.
In the 1950's and 60's huge and expensive research project to test every known substance, which is carried out in cancer cells. You may recall was discovered in Madagascar Periwinkle (Catharansus roseus), which revealed alkaloids (vinblastine and vincristine), which are still used in chemotherapy. Taxol, ovarian and breast cancer originates in the Pacific yew tree. The treatment for testicular cancer and small cell lung cancer called Etoposide 'was derived from the May apple. In "Plants used against cancer 'by Jonathan Hartwell over 3,000 plants identified by medical sources and folklore to treat cancer, of which about half were found to have any effect on cancer cells in test tubes.
When these plants are designer drugs, are chemicals only in isolation and the rest of the plant is usually discarded. The medically active compounds extracted from plants and modified until they are chemically unique. Then, the compound is patented, where a brand name and tested.
In the first phase, usually will be tested in animals, the second phase will determine the dosage levels and in phase 3, is tested in people. When approved by the Federal Drug Authority (USA) or Medicines and Health Regulation establishing the Agency (MHRA) in Britain, the cost of developing a new drug can reach five hundred million dollars, which was recovered the end consumer.
In addition to "targeted therapy" research as research chemicals that effect cancer cells, basic research continues, the differences between normal cells and cancer cells. In the past 30 years, this research has revealed much about our nature, but still no cure. Here are some chapters of scientific research on cancer.
Antibody-guided therapy: this is "magic bullet" of the original. Cancer researchers use monoclonal antibodies to carry poisons directly to cancer cells without harming others.
Chronobiology: much of what happens in our bodies is governed by cycles of the female cycle monthly cycle of brain waves. Human health depends on the interaction cycles adapted to acts of perception, respiration, reproduction and renewal. Chronobiology analyze these cycles over different times as day and night. Hormones, including stress and hormones, have their own bikes. For example, they may be at their peak of activity in the morning and calmer at night. Cancer cells seem not to obey the same cycle rate than normal cells.
Anti-telomerase: one part of a cell, called telomerase, regulates the life cycle of a cell and how many times it can reproduce. Some cancer cells escape this control and may increase the number of times they divide, becoming 'immortal'. Scientists hope to gain control of cancer cells by blocking the action of telomerase.
Anti-angiogenesis: secondary tumors (metastases) may be folded around the cells to grow new blood vessels to feed tumors, to supply oxygen and nutrients for the growth of cancer. This process is called angiogenesis, and this research is to find a way to stop the signals from normal cells that start the process.
anti-adhesion molecules: the cancer cells arise tufts, as opposed to a petri dish, which is part of a more flat. When they appear to be cells of a quality that can withstand the treatment. This research examines the ways that you can block all cell aggregation, dissolving clumps of more effective therapy.
Anti-oncogene: some elements of DNA, called oncogenes that play an important role in promoting cancer growth. Drugs that interfere with the production of oncogenes may be useful in the treatment of cancer in the future.
Gene therapy: research the use of tumor suppressor genes underlines the British National Cancer Plan as an important factor. In essence, DNA fragments is inserted to replace missing or damaged genes, possibly preventing the development of cancer from someone who might be "high risk".
Vaccines: very quietly finding a cure for cancer generally has ruled on the other hand, finding a vaccine. The whole idea of a cure or a treatment that is "all the same" breaks the specific case, the chaotic conditions that cause cancer in an individual. After billions in research and the Holy Grail of cancer therapy, research now is to find a vaccine.
In a recent conference in cancer immunologists immunology U.S. more than 21 countries participated in conferences on subjects such as immunology later: cancer immunosurveillance, immunoediting, the cancer antigen discovery, control and analysis of the immune response to cancer in humans, the development of cancer vaccines.
Cancer Vaccine Collaborative (CVC) was launched to much excitement. This is a unique research program to improve the way vaccines are developed against cancer, based on a collaboration of six medical centers in New York and Minnesota. The aim of their research is how to effectively immunize against cancer using a vaccine that uses "action research".
Vaccines made from donor blood have been proven to work for certain cancers. The experiments of bone marrow transplants show there are about 40,000 different fabrics, it is difficult to find a match. Usually a perfect match can be found in the immediate family of the patient. Bad matches can create a host of secondary dis-plains. Scientist are finding ways to train killer T cells taken either from the host or a donor, to better attack cancer cells. They noted that donors Killer T-cells that are already "primed" for a particular cancer (eg, cells of the body donors to "remember" of the disease) can be very effective. It may take several years to prove the validity, reliability, safety and efficacy of this treatment. Harvesting the natural immunity of our own cells or donor using gene technology may well become a major player against the immune system attacks the modern dis-plains.
Increased screening: this type of research will examine individuals who may be genetically at high risk of certain cancers and is part of preparation for possible vaccines. Genetic counseling is intended to be 21st century health care based on prevention of the disease, even better.
Combinations: the search for West Germany (Big Sart-Maticek) argues that there is no single cause for cancer, similar to the model of more chronic disease. It shows that there are environmental, psychological and spiritual disease. This means that treatment should be level and that a single treatment is likely to be effective because there is no single cause. This observation links with the position of holistic practitioners often have a broader view of health than orthodox doctors.
Dr. Robert Buckman is an experienced cancer researcher, and author of the informative book: ". What you really need to know about cancer," he summarizes what he sees the current state of scientific research on cancer:
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